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参考文献

• Li Y, Song D, Song Y,et al. Iron-induced local complement component 3 (C3) up-regulation via non-canonical transforming growth factor (TGF)-β signaling in the retinal pigment epithelium. J Biol Chem. 2015; 290: 11918–11934.
  サンプル：ARPE-19 cell culture
• Zhang Y, Nester CM, Martin B, Skjoedt M-O, Meyer NC, Shao D, et al. Defining the complement biomarker profile of C3 glomerulopathy. Clin J Am Soc Nephrol CJASN. 2014;9:1876–1882. doi: 10.2215/CJN.01820214.
  サンプル：Plasma (Human, C3G)
• Eberhardt HU, Buhlmann D, Hortschansky P, Chen Q, Böhm S, Kemper MJ, et al. Human factor H-related protein 2 (CFHR2) regulates complement activation. PLoS One (2013) 8(11):e78617.10.1371/journal.pone.0078617
  サンプル：Serum (Human)
• Vasilev V. V., Noe R., Dragon-Durey M.-A., et al. Functional characterization of autoantibodies against complement component C3 in patients with lupus nephritis. Journal of Biological Chemistry. 2015;290(42):25343–25355.
  サンプル：Serum (Human, Purified IgG from normal donors and autoantibody positive patients)
• Micklisch S, Lin Y, Jacob S, et al. Age-related macular degeneration associated polymorphism rs10490924 in ARMS2 results in deficiency of a complement activator. Journal of Neuroinflammation. 2017;14:4.
  サンプル：Serum (Human, with ARMS2 protein)

• Marzia Buscema, Sofiya Matviykiv, Tamás Mészáros, Gabriela Gerganova, Andreas Weinberger, Ute Mettal, Dennis Mueller, Frederik Neuhaus, Etienne Stalder, Takashi Ishikawa, Rudolf Urbanics, Till Saxer, Thomas Pfohl, János Szebeni, Andreas Zumbuehl, Bert Müller, Immunological response to nitroglycerin-loaded shear-responsive liposomes in vitro and in vivo, Journal of Controlled Release, Volume 264, 2017, Pages 14-23
  サンプル：Serum (Porcine)

• Brouwer MC, Baas F, van der Ende A, van de Beek D (2013) Genetic Variation and Cerebrospinal Fluid Levels of Mannose Binding Lectin in Pneumococcal Meningitis Patients. PLOS ONE 8(5): e65151.
  サンプル：CSF (Human)
• Koopmans MM, Brouwer MC, Geldhoff M, et al. Cerebrospinal fluid inflammatory markers in patients with Listeria monocytogenes meningitis. BBA Clinical. 2014;1:44-51.
  サンプル：CSF (Human, Listeria meningitis)
• Peterson, S. L., Nguyen, H. X., Mendez, O. A., & Anderson, A. J. (2017). Complement Protein C3 Suppresses Axon Growth and Promotes Neuron Loss. Scientific Reports, 7, 12904.
  サンプル：Neuron cells (Mouse)
• Ignatius A, Schoengraf P, Kreja L, Liedert A, Recknagel S, Kandert S, et al. Complement C3a and C5a modulate osteoclast formation and inflammatory response of osteoblasts in synergism with IL-1β. J Cell Biochem. 2011. September;112(9):2594–605
  サンプル：Peripheral blood mononuclear cells (supernatent)
• Nguyen BN, Azimzadeh AM, Schroeder C, et al. Absence of Gal epitope prolongs survival of swine lungs in an ex vivo model of hyperacute rejection. Xenotransplantation. 2011;18(2):94–107.
  サンプル：Plasma (Human)
• Kamat P, Juon B, Jossen B, Gajanayake T, Rieben R, Vogelin E. Assessment of endothelium and inflammatory response at the onset of reperfusion injury in hand surgery. J Inflamm (Lond) 2012;9(1):18.
  サンプル：Plasma (Human)
• Owsley C, Huisingh C, Jackson GR, Curcio CA, Szalai AJ, Dashti N, Clark M, Rookard K, McCrory MA, Wright TT, et al. Associations between abnormal rod-mediated dark adaptation and health and functioning in older adults with normal macular health. Invest Ophthalmol Vis Sci. 2014;55:4776–4789. doi: 10.1167/iovs.14-14502.
  サンプル：Plasma (Human)
• Chen SF, Wang FM, Li ZY, Yu F, Zhao MH, Chen M. Plasma complement factor H is associated with disease activity of patients with ANCA-associated vasculitis. Arthritis Res Ther (2015) 17:129.10.1186/s13075-015-0656-8
  サンプル：Plasma (Human)
• Klikovits, T., Stockhammer, P., Laszlo, V., Dong, Y., Hoda, M. A., Ghanim, B., … Hegedus, B. (2017). Circulating complement component 4d (C4d) correlates with tumor volume, chemotherapeutic response and survival in patients with malignant pleural mesothelioma. Scientific Reports, 7, 16456.
  サンプル：Plasma (Human)
• Sewing, S., Roth, A. B., Winter, M., Dieckmann, A., Bertinetti-Lapatki, C., Tessier, Y., … Rothfuss, A. (2017). Assessing single-stranded oligonucleotide drug-induced effects in vitro reveals key risk factors for thrombocytopenia. PLoS ONE, 12(11), e0187574.
  サンプル：Plasma (Human)
• Wu, H., Jay, L., Lin, S., Han, C., Yang, S., Cataland, S.R. and Masias, C. (2020), Interrelationship between ADAMTS13 activity, von Willebrand factor, and complement activation in remission from immune‐mediated trhrombotic thrombocytopenic purpura. Br J Haematol. doi:10.1111/bjh.16415
  サンプル：Plasma (Human, immune‐mediated thrombotic thrombocytopenic purpura)
• Li Q., Song D., Wang F. Clinicopathological characteristics and outcomes of Chinese patients with scanty immune deposits lupus nephritis: a large cohort study from a single center. ScientificWorldJournal. 2014 Feb 4;2014:212597.
  サンプル：Plasma (Human, lupus nephritis)
• Arbesu I, Bucsaiova M, Fischer MB, Mannhalter C. Platelet-borne complement proteins and their role in platelet–bacteria interactions. J Thromb Haemost 2016; 14: 2241–52.
  サンプル：Plasma (Human, platelet concentrated)
• Miao D, Li DY, Chen M, Zhao MH. Platelets are activated in ANCA-associated vasculitis via thrombin-PARs pathway and can activate the alternative complement pathway. Arthritis Res Ther. (2017) 19:252.
  サンプル：Plasma (Human, Platelets in ANCA-AAV)
• Flierl MA, Gaudiani JL, Sabel AL, Long CS, Stahel PF, Mehler PS. Complement C3 serum levels in anorexia nervosa: a potential biomarker for the severity of disease? Annals of General Psychiatry. 2011;10:16.
  サンプル：Serum (Human)
• Eberhardt HU, Buhlmann D, Hortschansky P, Chen Q, Böhm S, Kemper MJ, et al. Human factor H-related protein 2 (CFHR2) regulates complement activation. PLoS One (2013) 8(11):e78617.10.1371/journal.pone.0078617
  サンプル：Serum (Human)
• Rittirsch D, Flierl MA, Nadeau BA, Day DE, Huber-Lang MS, Grailer JJ, et al. Zonulin as prehaptoglobin2 regulates lung permeability and activates the complement system. Am J Physiol Lung Cell Mol Physiol (2013) 304:72.10.1152/ajplung.00196.2012
  サンプル：Serum (Human)
• He Y, Scholes MA, Wiet GJ, Li Q, Clancy C, et al. (2013) Complement activation in pediatric patients with recurrent acute otitis media. Int J Pediatr Otorhinolaryngol 77: 911–917
  サンプル：Serum (Human), MEE
• Seregin SS, Hartman ZC, Appledorn DM, Godbehere S, Jiang H, et al. (2010) Novel adenovirus vectors ‘capsid-displaying' a human complement inhibitor. J Innate Immun 2: 353–359
  サンプル：Serum (Human), Serum (Primate)
• Zhang Y, Huang Q, Tang M, Zhang J, Fan W. Complement Factor H Expressed by Retinal Pigment Epithelium Cells Can Suppress Neovascularization of Human Umbilical Vein Endothelial Cells: An in vitro Study. PloS one. 2015;10:e0129945.
  サンプル：Serum (Human, ARPE-19 cells)
• Roumenina L. T. et al. . A prevalent C3 mutation in aHUS patients causes a direct C3 convertase gain of function. Blood 119, 4182–4191.
  サンプル：Serum (Human, exposed to GEnCs and HUVEC)
• Schwab J., Hammerschmidt C., Richter D., Skerka C., Matuschka F.R., Wallich R., Zipfel P.F., Kraiczy P. Borrelia valaisiana resist complement-mediated killing independently of the recruitment of immune regulators and inactivation of complement components. PLoS ONE. 2013;8:e53659
  サンプル：Serum (Human, incubated with Borrelia valaisiana)
• Sommaggio R, Bello-Gil D, Pérez-Cruz M, Brokaw JL, Máñez R, Costa C. Genetic engineering strategies to prevent the effects of antibody and complement on xenogeneic chondrocytes. Eur Cell Mater. 2015 Nov 18;30:258-70.
  サンプル：Serum (Human, Porcine articular chondrocytes)
• Cho, M. S., Vasquez, H. G., Rupaimoole, R., Pradeep, S., Wu, S., Zand, B., … Afshar-Kharghan, V. (2014). Autocrine Effects of Tumor-Derived Complement. Cell Reports, 6(6), 1085–1095.
  サンプル：SKOV3ip1 cells
• Huang J, Cui Z, Gu QH, et al. Complement activation profile of patients with primary focal segmental glomerulosclerosis. PLoS One. 2020;15(6):e0234934. Published 2020 Jun 22. doi:10.1371/journal.pone.0234934
  サンプル：Plasma, Urine (Human, focal segmental glomerulosclerosis)

• Brouwer MC, Baas F, van der Ende A, van de Beek D (2013) Genetic Variation and Cerebrospinal Fluid Levels of Mannose Binding Lectin in Pneumococcal Meningitis Patients. PLOS ONE 8(5): e65151.
  サンプル：CSF (Human)
• Koopmans MM, Brouwer MC, Geldhoff M, et al. Cerebrospinal fluid inflammatory markers in patients with Listeria monocytogenes meningitis. BBA Clinical. 2014;1:44-51.
  サンプル：CSF (Human, Listeria meningitis)
• Merel M. Koopmans, Matthijs C. Brouwer, Madelijn Geldhoff, Mercedes Valls Seron, Judith Houben, Arie van der Ende, Diederik van de Beek, Cerebrospinal fluid inflammatory markers in patients with Listeria monocytogenes meningitis, In BBA Clinical, Volume 1, 2014, Pages 44-51, ISSN 2214-6474
  サンプル：CSF (Human, Listeria meningitis)
• Franca A, Aggarwal P, Barsov EV, Kozlov SV, Dobrovolskaia MA, Gonzalez-Fernandez A. Macrophage scavenger receptor A mediates the uptake of gold colloids by macrophages in vitro. Nanomedicine (Lond) 2011;6:1175–1188.
  サンプル：Plasma (Human)
• Schramm EC, Staten NR, Zhang Z, Bruce SS, Kellner C, Atkinson JP, et al. A quantitative lateral flow assay to detect complement activation in blood. Anal Biochem 2015;477:78–85.
  サンプル：Plasma (Human)
• Lashkari K, Teague G, Chen H, Lin YQ, Kumar S, et al. (2018) A monoclonal antibody targeting amyloid β (Aβ) restores complement factor I bioactivity: Potential implications in age-related macular degeneration and Alzheimer’s disease. PLOS ONE 13(5): e0195751.
  サンプル：Plasma (Human, AMD & Alzheimer's)
• Liu, C.-F., Min, X.-Y., Wang, N., Wang, J.-X., Ma, N., Dong, X., … Li, K. (2017). Complement Receptor 3 Has Negative Impact on Tumor Surveillance through Suppression of Natural Killer Cell Function. Frontiers in Immunology, 8, 1602.
  サンプル：Serum (Human)
• Zhou J, Kim SR, Westlund BS, Sparrow JR. Complement activation by bisretinoid constituents of RPE lipofuscin. Investig. Ophthalmol. Vis. Sci. 2009;50:1392–1399.
  サンプル：Serum (Human)
• Kim H, Meyer K, Di Bisceglie AM, Ray R. Inhibition of C3 Convertase Activity by Hepatitis C Virus as an Additional Lesion in the Regulation of Complement Components. Kaushik-Basu N, ed. PLoS ONE. 2014;9(7):e101422.
  サンプル：Serum (Human, with HCV)
• Muroya T, Kannan L, Ghiran IC, Shevkoplyas SS, Paz Z, et al. (2014) C4d deposits on the surface of RBCs in trauma patients and interferes with their function. Crit Care Med 42: e364–372.
  サンプル：Serum (Human, with Trauma)

• Owsley C, Huisingh C, Jackson GR, Curcio CA, Szalai AJ, Dashti N, Clark M, Rookard K, McCrory MA, Wright TT, et al. Associations between abnormal rod-mediated dark adaptation and health and functioning in older adults with normal macular health. Invest Ophthalmol Vis Sci. 2014;55:4776–4789. doi: 10.1167/iovs.14-14502.
  サンプル：Plasma (Human)
• Chan AS, Jonas A, Qui X, Ottoson NR, Walsh RM, Gorden KB, Harrison B, Maimonis PJ, Leonardo SM, Ertelt KE, Danielson ME, Michel KS, Nelson M, Graff JR, Patchen ML, Bose N. Imprime PGG-mediated anti-cancer immune activation requires immune complex formation. PLoS One. 2016;11 doi: 10.1371/journal.pone.0165909.
  サンプル：Plasma (Human, Imprime yeast treated)
• Bose N, Chan ASH, Guerrero F, et al. Binding of Soluble Yeast β-Glucan to Human Neutrophils and Monocytes is Complement-Dependent. Frontiers in Immunology. 2013;4:230.
  サンプル：Serum (Human)
• He Y, Scholes MA, Wiet GJ, Li Q, Clancy C, et al. (2013) Complement activation in pediatric patients with recurrent acute otitis media. Int J Pediatr Otorhinolaryngol 77: 911–917
  サンプル：Serum (Human), MEE
• Spirig R., Campbell I. K., Koernig S., Chen C.-G., Lewis B. J. B., Butcher R., Muir I., Taylor S., Chia J., Leong D., et al. 2018. rIgG1 Fc hexamer inhibits antibody-mediated autoimmune disease via effects on complement and FcγRs. J. Immunol. 200: 2542–2553.
  サンプル：Serum (Human, Fc activation)

• Keir L.S., Firth R., Aponik L., Feitelberg D., Sakimoto S., Aguilar E., Welsh G.I., Richards A., Usui Y., Satchell S.C. VEGF regulates local inhibitory complement proteins in the eye and kidney. J. Clin. Invest. 2017;127:199–214
  サンプル：Aquious Humor (Human)
• Brouwer MC, Baas F, van der Ende A, van de Beek D (2013) Genetic Variation and Cerebrospinal Fluid Levels of Mannose Binding Lectin in Pneumococcal Meningitis Patients. PLOS ONE 8(5): e65151.
  サンプル：CSF (Human)
• Koopmans MM, Brouwer MC, Geldhoff M, et al. Cerebrospinal fluid inflammatory markers in patients with Listeria monocytogenes meningitis. BBA Clinical. 2014;1:44-51.
  サンプル：CSF (Human, Listeria meningitis)
• Braunschweig A, Józsi M. Human pentraxin 3 binds to the complement regulator c4b-binding protein. PLoS One (2011) 6:e23991.10.1371/journal.pone.0023991
  サンプル：Fibroblast cells (Human)
• Owsley C, Huisingh C, Jackson GR, Curcio CA, Szalai AJ, Dashti N, Clark M, Rookard K, McCrory MA, Wright TT, et al. Associations between abnormal rod-mediated dark adaptation and health and functioning in older adults with normal macular health. Invest Ophthalmol Vis Sci. 2014;55:4776–4789. doi: 10.1167/iovs.14-14502.
  サンプル：Plasma (Human)
• TScambi C, Ugolini S, Jokiranta TS, De Franceschi L, Bortolami O, et al. (2015) The Local Complement Activation on Vascular Bed of Patients with Systemic Sclerosis: A Hypothesis-Generating Study. PLOS ONE 10(2): e0114856.
  サンプル：Plasma (Human)
• Veszeli N, Csuka D, Zotter Z, et al. Neutrophil activation during attacks in patients with hereditary angioedema due to C1-inhibitor deficiency. Orphanet Journal of Rare Diseases. 2015;10:156.
  サンプル：Plasma (Human)
• Chen SF, Wang FM, Li ZY, Yu F, Zhao MH, Chen M. Plasma complement factor H is associated with disease activity of patients with ANCA-associated vasculitis. Arthritis Res Ther (2015) 17:129.10.1186/s13075-015-0656-8
  サンプル：Plasma (Human)
• Sewing, S., Roth, A. B., Winter, M., Dieckmann, A., Bertinetti-Lapatki, C., Tessier, Y., … Rothfuss, A. (2017). Assessing single-stranded oligonucleotide drug-induced effects in vitro reveals key risk factors for thrombocytopenia. PLoS ONE, 12(11), e0187574.
  サンプル：Plasma (Human)
• Zhang Y, Nester CM, Martin B, Skjoedt M-O, Meyer NC, Shao D, et al. Defining the complement biomarker profile of C3 glomerulopathy. Clin J Am Soc Nephrol CJASN. 2014;9:1876–1882. doi: 10.2215/CJN.01820214.
  サンプル：Plasma (Human, C3G)
• Chan AS, Jonas A, Qui X, Ottoson NR, Walsh RM, Gorden KB, Harrison B, Maimonis PJ, Leonardo SM, Ertelt KE, Danielson ME, Michel KS, Nelson M, Graff JR, Patchen ML, Bose N. Imprime PGG-mediated anti-cancer immune activation requires immune complex formation. PLoS One. 2016;11 doi: 10.1371/journal.pone.0165909.
  サンプル：Plasma (Human, Imprime yeast treated)
• Li Q., Song D., Wang F. Clinicopathological characteristics and outcomes of Chinese patients with scanty immune deposits lupus nephritis: a large cohort study from a single center. ScientificWorldJournal. 2014 Feb 4;2014:212597.
  サンプル：Plasma (Human, lupus nephritis)
• Arbesu I, Bucsaiova M, Fischer MB, Mannhalter C. Platelet-borne complement proteins and their role in platelet–bacteria interactions. J Thromb Haemost 2016; 14: 2241–52.
  サンプル：Plasma (Human, platelet concentrated)
• Miao D, Li DY, Chen M, Zhao MH. Platelets are activated in ANCA-associated vasculitis via thrombin-PARs pathway and can activate the alternative complement pathway. Arthritis Res Ther. (2017) 19:252.
  サンプル：Plasma (Human, Platelets in ANCA-AAV)
• Agarwal S, et al. 2011. Linkage specificity and role of properdin in activation of the alternative complement pathway by fungal glycans. mBio 2(5):e00178-11.
  サンプル：Serum (Human)
• Whitehead B, Wu L, Hvam ML, et al. Tumour exosomes display differential mechanical and complement activation properties dependent on malignant state: implications in endothelial leakiness. J Extracell Vesicles. 2015;4:29685.
  サンプル：Serum (Human)
• Wang G, Chen F, Banda NK, et al. Activation of Human Complement System by Dextran-Coated Iron Oxide Nanoparticles Is Not Affected by Dextran/Fe Ratio, Hydroxyl Modifications, and Crosslinking. Frontiers in Immunology. 2016;7:418.
  サンプル：Serum (Human)
• He Y, Scholes MA, Wiet GJ, Li Q, Clancy C, et al. (2013) Complement activation in pediatric patients with recurrent acute otitis media. Int J Pediatr Otorhinolaryngol 77: 911–917
  サンプル：Serum (Human), MEE
• Roumenina L. T. et al. . A prevalent C3 mutation in aHUS patients causes a direct C3 convertase gain of function. Blood 119, 4182–4191.
  サンプル：Serum (Human, exposed to GEnCs and HUVEC)
• Spirig R., Campbell I. K., Koernig S., Chen C.-G., Lewis B. J. B., Butcher R., Muir I., Taylor S., Chia J., Leong D., et al. 2018. rIgG1 Fc hexamer inhibits antibody-mediated autoimmune disease via effects on complement and FcγRs. J. Immunol. 200: 2542–2553.
  サンプル：Serum (Human, Fc activation)
• Pironkova RP, Giamelli J, Seiden H, Parnell VA, Gruber D, Sison CP, Kowal C, Ojamaa K. Brain injury with systemic inflammation in newborns with congenital heart disease undergoing heart surgery. Exp Ther Med. 2017;14:228–38.
  サンプル：Serum (Human, Newborn Brain Injury)
• Sommaggio R, Bello-Gil D, Pérez-Cruz M, Brokaw JL, Máñez R, Costa C. Genetic engineering strategies to prevent the effects of antibody and complement on xenogeneic chondrocytes. Eur Cell Mater. 2015 Nov 18;30:258-70.
  サンプル：Serum (Human, Porcine articular chondrocytes)
• Huang J, Cui Z, Gu QH, et al. Complement activation profile of patients with primary focal segmental glomerulosclerosis. PLoS One. 2020;15(6):e0234934. Published 2020 Jun 22. doi:10.1371/journal.pone.0234934
  サンプル：Serum (Human, Porcine articular chondrocytes)

• Thurman J.M., Renner B., Kunchithapautham K., Ferreira V.P., Pangburn M.K., Ablonczy Z., Tomlinson S., Holers V.M., Rohrer B. Oxidative stress renders retinal pigment epithelial cells susceptible to complement-mediated injury. J. Biol. Chem. 2009;284:16939–16947
  サンプル：ARPE-19 Cells (in NHS)
• Brouwer MC, Baas F, van der Ende A, van de Beek D (2013) Genetic Variation and Cerebrospinal Fluid Levels of Mannose Binding Lectin in Pneumococcal Meningitis Patients. PLOS ONE 8(5): e65151.
  サンプル：CSF (Human)
• Koopmans MM, Brouwer MC, Geldhoff M, et al. Cerebrospinal fluid inflammatory markers in patients with Listeria monocytogenes meningitis. BBA Clinical. 2014;1:44-51.
  サンプル：CSF (Human, Listeria meningitis)
• Mizuno M, Suzuki Y, Higashide K, Sei Y, Iguchi D, Sakata F, et al. High levels of soluble C5b-9 complex in dialysis fluid may predict poor prognosis in peritonitis in peritoneal dialysis patients. PLoS One (2017) 12:e0169111.10.1371/journal.pone.0169111
  サンプル：Peritoneal dialysis fluid (PDF)
• Somani R, Richardson VR, Standeven KF, Grant PJ, Carter AM. Elevated Properdin and Enhanced Complement Activation in First-Degree Relatives of South Asian Subjects With Type 2 Diabetes. Diabetes Care. 2012;35(4):894-899.
  サンプル：Plasma (Human)
• Chowdhury SM, Kanakia S, Toussaint JD, et al. In Vitro Hematological and In Vivo Vasoactivity Assessment of Dextran Functionalized Graphene. Scientific Reports. 2013;3:2584.
  サンプル：Plasma (Human)
• Chen SF, Wang FM, Li ZY, Yu F, Zhao MH, Chen M. Plasma complement factor H is associated with disease activity of patients with ANCA-associated vasculitis. Arthritis Res Ther (2015) 17:129.10.1186/s13075-015-0656-8
  サンプル：Plasma (Human)
• Zhang Y, Nester CM, Martin B, Skjoedt M-O, Meyer NC, Shao D, et al. Defining the complement biomarker profile of C3 glomerulopathy. Clin J Am Soc Nephrol CJASN. 2014;9:1876–1882. doi: 10.2215/CJN.01820214.
  サンプル：Plasma (Human, C3G)
• Wu, H., Jay, L., Lin, S., Han, C., Yang, S., Cataland, S.R. and Masias, C. (2020), Interrelationship between ADAMTS13 activity, von Willebrand factor, and complement activation in remission from immune‐mediated trhrombotic thrombocytopenic purpura. Br J Haematol. doi:10.1111/bjh.16415
  サンプル：Plasma (Human, immune‐mediated thrombotic thrombocytopenic purpura)
• Chan AS, Jonas A, Qui X, Ottoson NR, Walsh RM, Gorden KB, Harrison B, Maimonis PJ, Leonardo SM, Ertelt KE, Danielson ME, Michel KS, Nelson M, Graff JR, Patchen ML, Bose N. Imprime PGG-mediated anti-cancer immune activation requires immune complex formation. PLoS One. 2016;11 doi: 10.1371/journal.pone.0165909.
  サンプル：Plasma (Human, Imprime yeast treated)
• Li Q., Song D., Wang F. Clinicopathological characteristics and outcomes of Chinese patients with scanty immune deposits lupus nephritis: a large cohort study from a single center. ScientificWorldJournal. 2014 Feb 4;2014:212597.
  サンプル：Plasma (Human, lupus nephritis)
• Miao D, Li DY, Chen M, Zhao MH. Platelets are activated in ANCA-associated vasculitis via thrombin-PARs pathway and can activate the alternative complement pathway. Arthritis Res Ther. (2017) 19:252.
  サンプル：Plasma (Human, Platelets in ANCA-AAV)
• Manzi, S. Rairie, J. et al. Sensitivity and Specificity of plasma and urine complement split products as indicators of lupus disease activity, Arthritis and Rheumatism 39(7)1178-1188, 1996.
  サンプル：Plasma (Human, SLE)
• Ferraris, J. R., Ferraris, V., Acquier, A. B., Sorroche, P. B., Saez, M. S., Ginaca, A., & Mendez, C. F. (2015). Activation of the alternative pathway of complement during the acute phase of typical haemolytic uraemic syndrome. Clinical and Experimental Immunology, 181(1), 118–125.
  サンプル：Plasma (Human, Stx-HUS)
• Senbagavalli P, Anuradha R, Ramanathan VD, Kumaraswami V, Nutman TB, Babu S. Heightened measures of immune complex and complement function and immune complex-mediated granulocyte activation in human lymphatic filariasis. Am J Trop Med Hyg. 2011;85:89–96.
  サンプル：Plasma (Human, with Lymphatic filariasis)
• Flierl MA, Gaudiani JL, Sabel AL, Long CS, Stahel PF, Mehler PS. Complement C3 serum levels in anorexia nervosa: a potential biomarker for the severity of disease? Annals of General Psychiatry. 2011;10:16.
  サンプル：Serum (Human)
• Bose N, Chan ASH, Guerrero F, et al. Binding of Soluble Yeast β-Glucan to Human Neutrophils and Monocytes is Complement-Dependent. Frontiers in Immunology. 2013;4:230.
  サンプル：Serum (Human)
• Le Lamer S, Paradis S, Rahmouni H, et al. Translation of TRO40303 from myocardial infarction models to demonstration of safety and tolerance in a randomized Phase I trial. Journal of Translational Medicine. 2014;12:38.
  サンプル：Serum (Human)
• Whitehead B, Wu L, Hvam ML, et al. Tumour exosomes display differential mechanical and complement activation properties dependent on malignant state: implications in endothelial leakiness. J Extracell Vesicles. 2015;4:29685.
  サンプル：Serum (Human)
• Blom AM, Corvillo F, Magda M, et al. Testing the Activity of Complement Convertases in Serum/Plasma for Diagnosis of C4NeF-Mediated C3 Glomerulonephritis. Journal of Clinical Immunology. 2016;36:517-527.
  サンプル：Serum (Human)
• Segura-Cervantes E, Mancilla-Ramírez J, González-Canudas J, et al. Inflammatory Response in Preterm and Very Preterm Newborns with Sepsis. Mediators of Inflammation. 2016;2016:6740827.
  サンプル：Serum (Human)
• Wang G, Chen F, Banda NK, et al. Activation of Human Complement System by Dextran-Coated Iron Oxide Nanoparticles Is Not Affected by Dextran/Fe Ratio, Hydroxyl Modifications, and Crosslinking. Frontiers in Immunology. 2016;7:418.
  サンプル：Serum (Human)
• Lukas K, Stadtherr K, Gessner A, et al. Effect of Immobilized Antithrombin III on the Thromboresistance of Polycarbonate Urethane. Boccaccini AR, ed. Materials. 2017;10(4):335.
  サンプル：Serum (Human)
• Marzia Buscema, Sofiya Matviykiv, Tamás Mészáros, Gabriela Gerganova, Andreas Weinberger, Ute Mettal, Dennis Mueller, Frederik Neuhaus, Etienne Stalder, Takashi Ishikawa, Rudolf Urbanics, Till Saxer, Thomas Pfohl, János Szebeni, Andreas Zumbuehl, Bert Müller, Immunological response to nitroglycerin-loaded shear-responsive liposomes in vitro and in vivo, Journal of Controlled Release, Volume 264, 2017, Pages 14-23
  サンプル：Serum (Human)
• He Y, Scholes MA, Wiet GJ, Li Q, Clancy C, et al. (2013) Complement activation in pediatric patients with recurrent acute otitis media. Int J Pediatr Otorhinolaryngol 77: 911–917
  サンプル：Serum (Human), MEE
• Pozsgay J, Babos F, Uray K, et al. In vitro eradication of citrullinated protein specific B-lymphocytes of rheumatoid arthritis patients by targeted bifunctional nanoparticles. Arthritis Research & Therapy. 2016;18:15.
  サンプル：Serum (Human, Coated Nano-Particles)
• Banda NK, Mehta G, Chao Y, et al. Mechanisms of complement activation by dextran-coated superparamagnetic iron oxide (SPIO) nanoworms in mouse versus human serum. Part Fibre Toxicol 2014; 11:64.
  サンプル：Serum (Human, dextran-coated superparamagnetic iron oxide (SPIO) nanoworms)
• Roumenina L. T. et al. . A prevalent C3 mutation in aHUS patients causes a direct C3 convertase gain of function. Blood 119, 4182–4191.
  サンプル：Serum (Human, exposed to GEnCs and HUVEC)
• Spirig R., Campbell I. K., Koernig S., Chen C.-G., Lewis B. J. B., Butcher R., Muir I., Taylor S., Chia J., Leong D., et al. 2018. rIgG1 Fc hexamer inhibits antibody-mediated autoimmune disease via effects on complement and FcγRs. J. Immunol. 200: 2542–2553.
  サンプル：Serum (Human, Fc activation)
• Pironkova RP, Giamelli J, Seiden H, Parnell VA, Gruber D, Sison CP, Kowal C, Ojamaa K. Brain injury with systemic inflammation in newborns with congenital heart disease undergoing heart surgery. Exp Ther Med. 2017;14:228–38.
  サンプル：Serum (Human, Newborn Brain Injury)
• Villas Boas IM, Pidde-Queiroz G, Magnoli FC, Gonçalves-de-Andrade RM, van den Berg CW, et al. (2015) A Serine Protease Isolated from the Bristles of the Amazonic Caterpillar, Premolis semirufa, Is a Potent Complement System Activator. PLOS ONE 10(3): e0118615.
  サンプル：Serum (Human, Premolis semirufa, caterpillar, bristle extract)
• Marie Delafontaine, Isadora Maria Villas-Boas, Giselle Pidde, et al., “Venom from Bothrops lanceolatus, a Snake Species Native to Martinique, Potently Activates the Complement System,” Journal of Immunology Research, vol. 2018, Article ID 3462136, 11 pages, 2018.
  サンプル：Serum (Human, with B. lanceolatus venom)
• Relizani K, Griffith G, Echevarría L, et al. Efficacy and Safety Profile of Tricyclo-DNA Antisense Oligonucleotides in Duchenne Muscular Dystrophy Mouse Model. Molecular Therapy Nucleic Acids. 2017;8:144-157.
  サンプル：Serum (Mouse)
• Huang J, Cui Z, Gu QH, et al. Complement activation profile of patients with primary focal segmental glomerulosclerosis. PLoS One. 2020;15(6):e0234934. Published 2020 Jun 22. doi:10.1371/journal.pone.0234934
  サンプル：Plasma, Urine (Human, focal segmental glomerulosclerosis)